A Visual Two-Choice Rule-Switch Task for Head-Fixed Mice
نویسندگان
چکیده
منابع مشابه
Innovative Methodology Choice ball: a response interface for two-choice psychometric discrimination in head-fixed mice
Sanders JI, Kepecs A. Choice ball: a response interface for twochoice psychometric discrimination in head-fixed mice. J Neurophysiol 108: 3416–3423, 2012. First published September 26, 2012; doi:10.1152/jn.00669.2012.—The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparati...
متن کاملChoice ball: a response interface for two-choice psychometric discrimination in head-fixed mice.
The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparations provide an unparalleled opportunity to observe and control neural circuits. To investigate how neural circuits produce behavior, these methods need to be paired with equally well-controlled and monitored behavioral...
متن کاملBall : a response interface for two - choice psychometric 2 discrimination in head - fixed mice
24 The mouse is an important model system for investigating the neural circuits 25 mediating behavior. Due to advances in imaging and optogenetic methods, head26 fixed mouse preparations provide an unparalleled opportunity to observe and 27 control neural circuits. In order to investigate how neural circuits produce 28 behavior, these methods need to be paired with equally well-controlled and 2...
متن کاملA self-initiated two-alternative forced choice paradigm for head-fixed mice
Psychophysical tasks for non-human primates have been instrumental in studying circuits underlying perceptual decision-making. To obtain greater experimental flexibility, these tasks have subsequently been adapted for use in freely moving rodents. However, advances in functional imaging and genetic targeting of neuronal populations have made it critical to develop similar tasks for head-fixed m...
متن کاملHigh-Yield Methods for Accurate Two-Alternative Visual Psychophysics in Head-Fixed Mice
Research in neuroscience increasingly relies on the mouse, a mammalian species that affords unparalleled genetic tractability and brain atlases. Here, we introduce high-yield methods for probing mouse visual decisions. Mice are head-fixed, facilitating repeatable visual stimulation, eye tracking, and brain access. They turn a steering wheel to make two alternative choices, forced or unforced. L...
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ژورنال
عنوان ژورنال: Frontiers in Behavioral Neuroscience
سال: 2019
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2019.00119